knee-osteoarthritis
Pycnogenol, a pine bark extract from the French maritime pine tree has been shown to reduce overall knee osteoarthritis symptoms by 20.9 percent, and lower pain by 40.3 percent, in a third clinical trial on osteoarthritis treatment with Pycnogenol.
It’s estimated by the Center for Disease Control that 34 percent of all adults over the age of 65 are affected by osteoarthritis, and that 26.9 million adults in the U.S. had osteoarthritis in 2005.
Osteoarthritis mostly affects cartilage, the hard slippery tissue that covers the ends of bones where they meet to form a joint. Healthy cartilage allows bones to glide over one another. It also absorbs energy from the shock of physical movement. In osteoarthritis, the surface layer of cartilage breaks down and wears away.
This allows bones under the cartilage to rub together, causing pain, swelling, and loss of motion of the joint. Over time, the joint may lose its normal shape. Also, small deposits of bone, called osteophytes or bone spurs, may grow on the edges of the joint. Bits of bone or cartilage can break off and float inside the joint space. This causes more pain and damage.
Pycnogenol acts as an anti-inflammatory and the study also suggests that Pycnogenol may assist the joints in recovery. The 3-month study involved 100 patients with stage I or II osteoarthritis, and were supplemented with either 150 mg Pycnogenol or placebo every day.
Overall knee osteoarthritis symptoms improved showed a significant 20.9 percent improvement in the Pycnogenol group, with joint improvement persisting for 4 weeks after intake of Pycnogenol was discontinued. After the 3-month trial was completed there was a 40.3 percent reduction in joint pain, 2 weeks later the pain was still 36.1 percent lower.
The patients supplementing with Pycnogenol also required significantly less analgesic medication compared to the placebo group. Source: Dr. Peter Rohdewald and Research Team. Slovakia’s Comenius University School of Medicine
The doctors in Pakistan prescribe Glucosamie in different combinations for osteosrthiritis. But this study shows them to be ineffective.
In a two-year multicenter study led by University of Utah doctors, the dietary supplements glucosamine and chondroitin sulfate performed no better than placebo in slowing the rate of cartilage loss in the knees of osteoarthritis patients.
This was an ancillary study concurrently conducted on a subset of the patients who were enrolled in the prospective, randomized GAIT (Glucosamine/chondroitin Arthritis Intervention Trial). The primary objective of this ancillary study was to investigate whether these dietary supplements could diminish the structural damage of osteoarthritis. The results, published in the October issue of Arthritis & Rheumatism, show none of the agents had a clinically significant effect on slowing the rate of joint space width loss —the distance between the ends of joint bones as shown by X-ray.
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Osteoarthritis can be a delibitating condition. Taking a nutritional supplement to alleviate the symptoms can be help. Just make sure you ask your doctor about it.